Under the patronage of Prof. Dr. Mamdouh Mostafa Ghorab, President of Suez Canal University and under the supervision of Prof. Magda Hagras, Vice President for Graduate Studies and Research, the doctoral thesis was presented to researcher /El- Hamali Ali Moftah Abdullah in the pharmaceutical sciences on Alzheimer’s disease. Lecturer in the Libyan Observatory of the University of Libya to obtain the degree of Doctor of Philosophy in Pharmaceutical Sciences, Department of Drugs and Toxins entitled “The Role of Nitric Oxide in Cell Death in Nosogen of Alzheimer’s Disease in Rats – Effect of Donyazil-Z-R-Jinin” on Wednesday, 18/4/2018. the Supervisory Committee consisted of Prof. Dr. Yasser Mustafa, Professor of Medicine and Toxins, Dean of the Faculty of Pharmacy, Suez Canal University, and Prof. Dr. Zakaria El-Khayyat, Professor of Biochemistry at the National Research Center, , Prof. Dr. Omar Mohamed Abdel Salam, Professor of Drugs, Department of Toxins and Drugs, National Research Center and Dr. Sawsan Abu Bakr Zaitoun Assistant Professor of Drugs and Toxicology, Faculty of Pharmacy, Suez Canal University. The committee was composed of Prof. Dr. Tarek Kamal Mutawa, Professor of Medical Biochemistry, Faculty of Pharmacy, Cairo University, Prof. Dr. Ahmed Mohamed Labib, Professor of Pharmacology, Faculty of Medicine, Al-Azhar University of Benin, prof.Dr. Yasser Mustafa, Dean of Faculty of Pharmacy, Suez Canal University, Medical Biochemistry at the National Research Center